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Covid-19: Blood Plasma Authorization Is Put on Hold

Last week, just as the Food and Drug Administration was preparing to issue an emergency authorization for blood plasma as a Covid-19 treatment, a group of top federal health officials including Dr. Anthony S. Fauci intervened, arguing that emerging data on the treatment was too weak, according to two senior administration officials.

The authorization is on hold for now as more data is reviewed, according to H. Clifford Lane, the clinical director at the National Institute of Allergy and Infectious Diseases. An emergency approval could still be issued in the near future, he said.

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Clinical Trials of Coronavirus Drugs Are Taking Longer Than Expected

 

As the coronavirus pandemic continues to wreak havoc in the United States and treatments are needed more than ever, clinical trials for some of the most promising experimental drugs are taking longer than expected.

Researchers at a dozen clinical trial sites said that testing delays, staffing shortages, space constraints and reluctant patients were complicating their efforts to test monoclonal antibodies, man-made drugs that mimic the molecular soldiers made by the human immune system.

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The Many Symptoms of Covid-19

For a Texas nurse, the first sign that something was wrong happened while brushing her teeth — she couldn’t taste her toothpaste. For a Georgia attorney, it was hitting a wall of fatigue on a normally easy run. When a Wisconsin professor fell ill in June, he thought a bad meal had upset his stomach.

But eventually, all of these people discovered that their manifold symptoms were all signs of Covid-19. Some of the common symptoms — a dry cough, a headache — can start so mildly they are at first mistaken for allergies or a cold. In other cases, the symptoms are so unusual — strange leg pain, a rash or dizziness — that patients and even their doctors don’t think Covid-19 could be the culprit.

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