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Clinical Trials of Coronavirus Drugs Are Taking Longer Than Expected

 

As the coronavirus pandemic continues to wreak havoc in the United States and treatments are needed more than ever, clinical trials for some of the most promising experimental drugs are taking longer than expected.

Researchers at a dozen clinical trial sites said that testing delays, staffing shortages, space constraints and reluctant patients were complicating their efforts to test monoclonal antibodies, man-made drugs that mimic the molecular soldiers made by the human immune system.

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New Zealand: 14 new Covid-19 cases reported after 102 days of no new cases

The detection of four new infected family members earlier this week shocked a country that had recorded no locally transmitted cases for more than three months.

Of the new cases, 13 have been linked back to this family, while one is an overseas arrival who was in quarantine.

A three-day lockdown was imposed in Auckland on Wednesday.

"We can see the seriousness of the situation we are in," Prime Minister Jacinda Ardern said in a news conference.

"It’s being dealt with in an urgent but calm and methodical way."

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The Many Symptoms of Covid-19

For a Texas nurse, the first sign that something was wrong happened while brushing her teeth — she couldn’t taste her toothpaste. For a Georgia attorney, it was hitting a wall of fatigue on a normally easy run. When a Wisconsin professor fell ill in June, he thought a bad meal had upset his stomach.

But eventually, all of these people discovered that their manifold symptoms were all signs of Covid-19. Some of the common symptoms — a dry cough, a headache — can start so mildly they are at first mistaken for allergies or a cold. In other cases, the symptoms are so unusual — strange leg pain, a rash or dizziness — that patients and even their doctors don’t think Covid-19 could be the culprit.

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Why the Coronavirus is More Likely to ‘Superspread’ Than the Flu

For a spiky sphere just 120 nanometers wide, the coronavirus can be a remarkably cosmopolitan traveler.

Spewed from the nose or mouth, it can rocket across a room and splatter onto surfaces; it can waft into poorly ventilated spaces and linger in the air for hours. At its most intrepid, the virus can spread from a single individual to dozens of others, perhaps even a hundred or more at once, proliferating through packed crowds in what is called a superspreading event.

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